Title of article
Microwave promoted amination of 3-bromoisoxazoles
Author/Authors
Moore، نويسنده , , Jane E. and Spinks، نويسنده , , Daniel and Harrity، نويسنده , , Joseph P.A. Harrity، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3189
To page
3191
Abstract
This Letter describes the amination of 3-bromoisoxazoles by a nucleophilic aromatic substitution reaction. We have found 3-bromoisoxazoles to be inert to substitution under thermal conditions, however, the employment of phosphazene bases under microwave irradiation facilitates the amination process and allows the corresponding 3-aminoisoxazoles to be isolated in moderate yield.
Keywords
microwave irradiation , BEMP , amination , Isoxazoles
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841308
Link To Document