Title of article
Diastereo- and enantioselective synthesis of a conagenin skeletal amide moiety
Author/Authors
Rodrigues، نويسنده , , J.Augusto R and Moran، نويسنده , , Paulo J.S and Milagre، نويسنده , , C??ntia D.F and Ursini، نويسنده , , Cleber V، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
3579
To page
3582
Abstract
A synthetic study was carried out to obtain epimers of a protected 2,4-dihydroxy-3-methylpentanoic ester 9, which is a central building block of the immunomodulator (+)-conagenin 1. The configuration of the three contiguous stereogenic centers was determined by NMR measurements and comparison with the stereogenic centers of lactone 10.
Keywords
conagenin , PHB-biopolymer , Hydrogenation , ?-methylene-?-keto ester
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841451
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