Title of article
Synthetic studies on thiostrepton family of peptide antibiotics: synthesis of the pentapeptide segment containing dihydroxyisoleucine, thiazoline and dehydroamino acid
Author/Authors
Shuhei Higashibayashi، نويسنده , , Shuhei and Kohno، نويسنده , , Mitsunori and Goto، نويسنده , , Taiji and Suzuki، نويسنده , , Kengo and Mori، نويسنده , , Tomonori and Hashimoto، نويسنده , , Kimiko and Nakata، نويسنده , , Masaya، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
3707
To page
3712
Abstract
The dihydroxyisoleucine-, thiazoline- and dehydroamino acid-containing pentapeptide of the thiostrepton family of peptide antibiotics was synthesized, which featured the β-lactone opening by phenylselenylation, the vinylzinc addition to the chiral sulfinimine, the Wipf oxazoline–thiazoline conversion method and the oxidative syn-elimination of the phenylseleno group.
Keywords
Thioamides , thiazolines , sulfinimines , Dihydroxyisoleucine , Thiostrepton
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841507
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