Title of article
A stereoselective synthesis for the (5Z,9Z)-14-methyl-5,9-pentadecadienoic acid and its monounsaturated analog (Z)-14-methyl-9-pentadecenoic acid
Author/Authors
Carballeira، نويسنده , , Néstor M. and Sanabria، نويسنده , , David and Ayala، نويسنده , , Norma L. and Cruz، نويسنده , , Clarisa، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3761
To page
3763
Abstract
A stereoselective synthesis for the (5Z,9Z)-14-methyl-5,9-pentadecadienoic acid and the monounsaturated analog (Z)-14-methyl-9-pentadecenoic acid was accomplished in six to seven steps where double alkyne coupling was the key step. This synthesis will facilitate the study of the topoisomerase I inhibitory profile of this important class of fatty acids.
Keywords
fatty acids , Topoisomerase I , Synthesis , Alkyne coupling
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841533
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