Author/Authors :
Marcaccini، نويسنده , , Stefano and Pepino، نويسنده , , Roberto and Pozo، نويسنده , , M.Cruz and Basurto، نويسنده , , Sara and Garc??a-Valverde، نويسنده , , Mar??a and Torroba، نويسنده , , Tom?s، نويسنده ,
Abstract :
A new application of the Ugi reaction in the synthesis of heterocyclic compounds is described. Substituted quinolin-2-(1H)-ones are formed in one-pot sequential Ugi four-component condensation and intramolecular Knoevenagel cyclization between o-acylanilines, aldehydes, malonic or tosylacetic acids and cyclohexyl isocyanide.
