Author/Authors :
Wittenberg، نويسنده , , Rüdiger and Beier، نويسنده , , Christian and Drنger، نويسنده , , Gerald and Jas، نويسنده , , Gerhard and Jasper، نويسنده , , Christian and Monenschein، نويسنده , , Holger and Kirschning، نويسنده , , Andreas، نويسنده ,
Abstract :
The first synthetic advances towards the novel diterpenoid tonantzitlolone 1 are described. The key steps in the synthesis involve a chromium(II) Reformatsky reaction, a diastereoselective C1 extension and an expeditious aldol coupling step of two advanced precursors.
Keywords :
terpene , Chromium Reformatsky reaction , polymer-supported reagents , total synthesis , Formylation
