Author/Authors :
Deprez-Poulain، نويسنده , , Rebecca and Willand، نويسنده , , Nicolas and Boutillon، نويسنده , , Christophe and Nowogrocki، نويسنده , , Guy and Azaroual، نويسنده , , Nathalie and Deprez، نويسنده , , Benoit، نويسنده ,
Abstract :
In order to mimic the complexity of natural products, we designed and obtained with simple synthetic methods, building blocks with `quaternary chiral centersʹ. These tricyclic lactams resulted from the reaction of a functional γ-keto-acid and various commercially available bi-nucleophiles.