Title of article
Application of the asymmetric aminohydroxylation reaction for the syntheses of HIV-protease inhibitor, hydroxyethylene dipeptide isostere and γ-amino acid derivative
Author/Authors
Sumedha Kondekar، نويسنده , , Nagendra B and Kandula، نويسنده , , Subba Rao V. and Kumar، نويسنده , , Pradeep، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
5477
To page
5479
Abstract
An enantioselective synthesis of lactone 1, a precursor to the (2R,4S,5S) hydroxyethylene dipeptide isostere and amino acid AHPPA 2 has been accomplished from the common intermediate 5 employing Sharpless asymmetric aminohydroxylation as the key step.
Keywords
Sharpless asymmetric aminohydroxylation , HIV-protease inhibitor , ?-Amino acid derivative , Hydroxyethylene dipeptide isostere
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842429
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