Author/Authors :
Colin، نويسنده , , Thomas and El Ka??m، نويسنده , , Laurent and Gaultier، نويسنده , , Laetitia and Grimaud، نويسنده , , Laurence and Gatay، نويسنده , , Laurent and Michaut، نويسنده , , Valérie، نويسنده ,
Abstract :
Hydrates of trifluoropyruvamides are readily obtained from isocyanides and trifluoroacetic anhydride. Under catalysis with secondary amines, these hydrates were successfully reacted with various methylketones to form fluorinated aldol type compounds. The effect of the amine is discussed as well as Henry type additions with nitromethane.
Keywords :
Pyruvamide , Trifluoromethyl group , isocyanide , enamines
