Title of article
Direct alkenylation of arylamines at the ortho-position
Author/Authors
Satoh، نويسنده , , Tsuyoshi and Ogino، نويسنده , , Yumi and Nakamura، نويسنده , , Masatomo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
5785
To page
5789
Abstract
Treatment of magnesium alkylidene carbenoids, which were generated from 1-chlorovinyl p-tolyl sulfoxides with isopropylmagnesium chloride at −78 °C in toluene, with N-lithio arylamines gave ortho-alkenylated arylamines in moderate to good yields. The reaction was found to proceed in a highly stereospecific manner at the carbenoid carbon. This reaction offers a quite novel and direct alkenylation of arylamines at the ortho-position of the aromatic ring.
Keywords
Sulfoxide–magnesium exchange reaction , Sulfoxide , magnesium alkylidene carbenoid , Alkenylation , ortho-Alkenylated arylamine
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842741
Link To Document