Author/Authors :
He، نويسنده , , Haiyin and Wang، نويسنده , , Ting-Zhong and Dushin، نويسنده , , Russell G and Feng، نويسنده , , Xidong and Shen، نويسنده , , Bo and Ashcroft، نويسنده , , Joseph S and Koehn، نويسنده , , Frank E and Carter، نويسنده , , Guy T، نويسنده ,
Abstract :
In structure–activity relationship (SAR) studies on mannopeptimycin antibiotics, mannopeptimycin α(1) was acetalized by reacting with certain dialkyl acetals under acidic conditions. The major products of these reactions were determined to be cyclic acetals at the 4,6-positions of the terminal mannose (Man-B), by exemplary spectroscopic analyses of two typical acetalization products 2 and 3.
