Title of article :
Novel trichothecanes, paecilomycine A, B, and C, isolated from entomopathogenic fungus, Paecilomyces tenuipes
Author/Authors :
Kikuchi، نويسنده , , Haruhisa and Miyagawa، نويسنده , , Yasuhiro and Sahashi، نويسنده , , Yuko and Inatomi، نويسنده , , Satoshi and Haganuma، نويسنده , , Asami and Nakahata، نويسنده , , Norimichi and Oshima، نويسنده , , Yoshiteru، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Paecilomycine A (1), B (2), and C (3) were isolated from cultivated fruiting bodies of Paecilomyces tenuipes (Isaria japonica), which is a popular entomopathogenic fungus used in folk medicine and health foods in China, Korea, and Japan. The structures of 1–3 were deduced from their spectroscopic data and their absolute configurations were elucidated by preparing their MPA esters. Compound 1 showed activity in the neurotrophic factor biosynthesis in glial cells.
Keywords :
Paecilomyces tenuipes , Trichothecane , PC-12 cell , glial cell
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
