Title of article
Alkoxy group facilitated ring closing metathesis (RCM) of acyclic 1,6-dienes. Convenient synthesis of non-racemic highly substituted cyclopentenols
Author/Authors
Nayek، نويسنده , , Abhijit and Banerjee، نويسنده , , Shyamapada and Sinha، نويسنده , , Saikat and Ghosh، نويسنده , , Subrata، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
6457
To page
6460
Abstract
Alkoxymethyl groups at the C-5 allylic position of 1,6-dienols have been found to accelerate RCM reactions significantly with the Grubbs’ catalyst PhCHRu(PCy3)2Cl2. This phenomenon has been used for direct access to highly substituted cyclopentenols, potential intermediates in the synthesis of carbovir, abacavir and BCA.
Keywords
nucleosides , cyclopentenes , asymmetric synthesis , metathesis
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843024
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