Author/Authors :
Allin، نويسنده , , Steven M. and Thomas، نويسنده , , Christopher I. and Allard، نويسنده , , James E. and Doyle، نويسنده , , Kevin and Elsegood، نويسنده , , Mark R.J.، نويسنده ,
Abstract :
We report a novel, facile and highly stereoselective approach to the indolo[2,3-a]quinolizine ring system from a readily available, non-racemic chiral template. We demonstrate the potential for application of this methodology to natural product synthesis through conversion of the template to a simple indole alkaloid with high enantiomeric purity.