In situ cyclopropanation: a rapid one-pot method for the synthesis of resin bound cyclopropyl phenyl methanones as combinatorial scaffolds

An efficient, high yielding one-pot synthesis of 4-substituted cyclopropyl phenyl methanones bound to RAM and WANG resins has been developed. The resin bound cyclopropyl phenyl methanone served as a combinatorial scaffold for the generation of structurally diverse alicyclic compounds.