Title of article :
Highly regioselective ring opening of epoxides using NaN3: a short and efficient synthesis of (−)-cytoxazone
Author/Authors :
Boruwa، نويسنده , , Joshodeep and Borah، نويسنده , , Jagat C. and Kalita، نويسنده , , Biswajit and Barua، نويسنده , , Nabin C.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
A convenient and efficient synthesis of 1,2-azido alcohols has been achieved by regioselective ring opening of epoxides using NaN3 and 4 Å molecular sieves in acetonitrile. The utility of this method has been demonstrated by achieving a short synthesis of (−)-cytoxazone in 48% overall yield.
Keywords :
molecular sieves , Azidoalcohol , (?)-Cytoxazone , regioselectivity
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
