• Title of article

    Mechanism of an unusual decarboxylative cyclization

  • Author/Authors

    Kende، نويسنده , , Andrew S. and Henry، نويسنده , , Olivier and Chen، نويسنده , , Zecheng Wang، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2004
  • Pages
    4
  • From page
    7809
  • To page
    7812
  • Abstract
    The mechanism of an unusual decarboxylative cyclization from 5-methoxy-1-(2-carboxyphenyl)-1,4-dihydro-4-oxopyridine-2-carboxylic acid (diacid) to 3-methoxypyrido[1,2-a]indole-2,10-dione (ketone) has been investigated. 13C-labeling has demonstrated that the carbonyl carbon of the ketone arises exclusively from the anthranilic acid carboxyl of the diacid. A zwitterionic mechanism has been proposed.
  • Keywords
    Mechanism , Decarboxylative cyclization
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2004
  • Journal title
    Tetrahedron Letters
  • Record number

    1843553