Title of article :
Diastereoselective Baylis–Hillman reaction: first use of chiral 2,3-epoxy aldehydes as novel electrophiles
Author/Authors :
Krishna، نويسنده , , Palakodety Radha and Lopinti، نويسنده , , Krishna Rao and Kannan، نويسنده , , V.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Chiral 2,3-epoxy aldehydes have been effectively utilized for the first time as novel electrophiles in Baylis–Hillman reactions with activated alkenes to result in densely functionalized adducts in good yields (61–80%) and in moderate to good diastereoselectivities (40–72% de).
Keywords :
2 , Diastereoselective Baylis–Hillman reaction , 3-Epoxy aldehyde , Chiral electrophile , Cornforth model , Activated alkene
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
