Title of article :
The synthesis of potential Neramexane metabolites: cis- and trans-3-amino-1,3,5,5-tetramethylcyclohexanecarboxylic acids
Author/Authors :
Dina Trifanova، نويسنده , , Dina and Trifonova، نويسنده , , Marija and Jirgensons، نويسنده , , Aigars and Kauss، نويسنده , , Valerjans and Pugovich، نويسنده , , Osvalds and Kalvinsh، نويسنده , , Ivars and Quack، نويسنده , , Guenter، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
A seven step synthetic route toward potential Neramexane metabolites cis- and trans-3-amino-1,3,5,5-tetramethylcyclohexanecarboxylic acids, cis-1 and trans-1, has been developed from isophorone. The synthetic procedure represents a useful method for the preparation of γ-amino acids with both amino and carboxyl groups situated at tertiary carbon atoms.
Keywords :
Neramexane , The Ritter reaction , metabolites , Oxidation , Latent carboxyl group
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
