Author/Authors :
Kiyota، نويسنده , , Hiromasa and Takai، نويسنده , , Takafumi and Saitoh، نويسنده , , Masatoshi and Nakayama، نويسنده , , Osamu and Oritani، نويسنده , , Takayuki and Kuwahara، نويسنده , , Shigefumi، نويسنده ,
Abstract :
A concise and high yielding synthesis of (−)-tabtoxinine-β-lactam 1, the cause of tobacco wildfire disease, was achieved from l-serine using a zinc-mediated coupling reaction, Sharpless asymmetric dihydroxylation and lactamization of N-OBn amide as the key steps.
