Title of article
Diastereo- and enantio-selective crotylation of α-ketoesters using crotyl boronic acid ester complexes
Author/Authors
Chen، نويسنده , , Yanping and Eltepu، نويسنده , , Laxman and Wentworth Jr.، نويسنده , , Paul، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
8285
To page
8288
Abstract
A diastereo- and enantio-selective crotylation of ethyl pyruvate has been achieved using a chiral boronic acid auxiliary-based approach. This reaction creates two contiguous stereogenic centers, one of which is a quaternary carbon with complete diastereoselectivity and with enantioselectivities up to 7:1 (73% ee).
Keywords
enantioselective , Boronic acid ester , asymmetric
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843753
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