Title of article
A versatile synthesis of fused triazolo derivatives by sequential Ugi/alkyne-azide cycloaddition reactions
Author/Authors
Irini Akritopoulou-Zanze، نويسنده , , Irini and Gracias، نويسنده , , Vijaya and Djuric، نويسنده , , Stevan W.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
8439
To page
8441
Abstract
We report a facile synthesis of fused dihydrotriazolo[1,5-a]pyrazinones and triazolobenzodiazepines by an Ugi/alkyne–azide cycloaddition synthetic sequence. The coupling of the Ugi multi-component reaction with the intramolecular alkyne–azide cycloaddition provides access to highly functionalized heterocyclic ring systems in two steps from easily available starting materials in excellent overall yields.
Keywords
Multi-component reactions , Ugi , Intramolecular azide–alkyne cycloaddition , Fused triazolo derivatives , 5-a]pyrazinones , Sequential Ugi/IAAC , Fused heterocycles , Triazolobenzodiazepines
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843826
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