Title of article :
Efficient guanylation of Nα,Nω-difunctionalized polyamines at the secondary amino functions
Author/Authors :
Athanassopoulos، نويسنده , , Constantinos M. and Garnelis، نويسنده , , Thomas and Pantazaka، نويسنده , , Evangelia and Papaioannou، نويسنده , , Dionissios، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Treatment of Nα,Nω-ditritylated linear and aromatic polyamines and of polyamine conjugates of the alkaloid kukoamine A (KukA) type with N,N′-bis(tert-butoxycarbonyl)thiourea in the presence of Mukaiyama’s reagent produced high yields of derivatives guanylated at the secondary amino functions.
Keywords :
Kukoamine A analogs , guanylation , Thiourea derivatives , Mukaiyama’s reagent , protecting groups , polyamines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
