Title of article
A simple and efficient radical reduction using water-soluble radical initiator and hypophosphorous acid in aqueous alcohol
Author/Authors
Nambu، نويسنده , , Hisanori and Alinejad، نويسنده , , Anahita Hessamian and Hata، نويسنده , , Kayoko and Fujioka، نويسنده , , Hiromichi and Kita، نويسنده , , Yasuyuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
8927
To page
8929
Abstract
A simple, mild, and high-yielding procedure for the reduction of various halogenated compounds using a combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] (VA-061), a water-soluble chain carrier, hypophosphorous acid, and the base, triethylamine, in aqueous alcohol is described. The reagents used in this method are all water soluble, and therefore, an almost pure desired product can be readily obtained using only an extraction procedure.
Keywords
radical reduction , The water-soluble radical initiator , Aqueous alcohol , Hypophosphorous acid
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844013
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