Title of article
N-Iodosuccinimide (NIS) as a mild and highly chemoselective catalyst for deprotection of tert-butyldimethylsilyl ethers
Author/Authors
Karimi، نويسنده , , Babak and Zamani، نويسنده , , Asghar and Zareyee، نويسنده , , Daryoush، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
9139
To page
9141
Abstract
A variety of alcoholic TBDMS (t-butyldimethylsilyl) ethers are easily removed in excellent yields by treatment with a catalytic amount of N-iodosuccinimide (NIS, 5 mol %) in methanol. This method is able to deprotect TBDMS ethers of alcohols in the presence of TBDMS ethers of phenols.
Keywords
Deprotection , Silyl ethers , N-iodosuccinimide , TBDMS ethers , protecting groups
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844101
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