Title of article
Catalytic asymmetric Pauson–Khand-type reactions of enynes with formaldehyde in aqueous media
Author/Authors
Fuji، نويسنده , , Koji and Morimoto، نويسنده , , Tsumoru and Tsutsumi، نويسنده , , Ken and Kakiuchi، نويسنده , , Kiyomi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
9163
To page
9166
Abstract
The first example of an aqueous, asymmetric, and CO gas-free Pauson–Khand-type reaction is described. Using formaldehyde as a commercially available substitute for carbon monoxide, combined use of a hydrophilic phosphine (TPPTS) and a hydrophobic, chiral phosphine (tolBINAP) enable the reaction to proceed smoothly in aqueous media, even in the absence of carbon monoxide, and stereoselectively.
Keywords
Pauson–Khand , Enynes , Asymmetric catalysis , Formaldehyde
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844109
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