Title of article
Ti(III)-induced radical cyclization. A stereoselective entry to the perhydrobenzo[e]indene unit of new protein farnesyltransferase inhibitors, andrastins A–D
Author/Authors
Toyota، نويسنده , , Masahiro and Okamoto، نويسنده , , Rei and Ogata، نويسنده , , Takeshi and Ihara، نويسنده , , Masataka، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
9203
To page
9205
Abstract
An efficient approach for the synthesis of a fully functionalized perhydrobenzo[e]indene, the BCD ring system of andrastins A–D, is described. The synthesis commences from (±)-Wieland–Miescher ketone and features a Ti(III)-induced radical cyclization as the central step.
Keywords
Ti(III)-induced radical cyclization , Andrastins , Protein farnesyltransferase inhibitor
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844125
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