Title of article
A novel oxidative side-chain transformation of α-amino acids and peptides by methyltrioxorhenium/H2O2 system
Author/Authors
Lazzaro، نويسنده , , Francesco and Crucianelli، نويسنده , , Marcello and De Angelis، نويسنده , , Francesco and Neri، نويسنده , , Veronica and Saladino، نويسنده , , Raffaele، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
9237
To page
9240
Abstract
N-Boc derivatives of Met, Cys, and Trp, the properties of which resemble those of the respective amino acid residues present in proteins, are efficiently oxidized by methyltrioxorhenium and H2O2. A high regioselectivity for the oxidation of these residues when embedded into peptides was also found.
Keywords
Amino acid side-chain oxidation , Homogeneous catalysis , Hydrogen peroxide , Methyltrioxorhenium
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844136
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