Author/Authors :
Dutta، نويسنده , , Rajat and Mandal، نويسنده , , Debayan and Panda، نويسنده , , Nilendu and Mondal، نويسنده , , Nirup B. and Banerjee، نويسنده , , Sukdeb and Kumar، نويسنده , , Shrabanti and Weber، نويسنده , , Manuela and Luger، نويسنده , , Peter and Sahu، نويسنده , , Niranjan P.، نويسنده ,
Abstract :
A one-pot synthesis of substituted oxazino-2-quinolones is described. The cornerstone of this methodology involves PTC catalyzed addition of an ethylene dihalide to a quinol to generate the corresponding O-alkylated intermediate in situ followed by ring closing and subsequent formation of a carbonyl group in the oxazinoquinolone in a one-pot sequence.