Author/Authors :
Popsavin، نويسنده , , Velimir and Grabe?، نويسنده , , Sanja and Popsavin، نويسنده , , Mirjana and Krsti?، نويسنده , , Ivana and Koji?، نويسنده , , Vesna and Bogdanovi?، نويسنده , , Gordana and Divjakovi?، نويسنده , , Vladimir، نويسنده ,
Abstract :
A new approach to the dephenyl goniofufurone analogue 2 and the corresponding (3S,4R)-stereoisomer 3 is reported. The resulting furanolactones 2 and 3 have shown a potent and selective in vitro cytotoxicity against certain human tumour cell lines.
Keywords :
Goniofufurone analogues , cytotoxicity , D-xylose , d-lyxose , Michael ring closure , Wittig reaction , Furanolactones
