Title of article
Wittig reaction with partially protected sugar lactol derivatives. Preparation of highly cytotoxic goniofufurone analogues
Author/Authors
Popsavin، نويسنده , , Velimir and Grabe?، نويسنده , , Sanja and Popsavin، نويسنده , , Mirjana and Krsti?، نويسنده , , Ivana and Koji?، نويسنده , , Vesna and Bogdanovi?، نويسنده , , Gordana and Divjakovi?، نويسنده , , Vladimir، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
9409
To page
9413
Abstract
A new approach to the dephenyl goniofufurone analogue 2 and the corresponding (3S,4R)-stereoisomer 3 is reported. The resulting furanolactones 2 and 3 have shown a potent and selective in vitro cytotoxicity against certain human tumour cell lines.
Keywords
Goniofufurone analogues , cytotoxicity , D-xylose , d-lyxose , Michael ring closure , Wittig reaction , Furanolactones
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844205
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