Title of article
Trimethylsilyl cyanide addition to aldimines and its application in the synthesis of (S)-phenylglycine methyl ester
Author/Authors
Prasad، نويسنده , , B.A. Bhanu and Bisai، نويسنده , , Alakesh and Singh، نويسنده , , Vinod K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
9565
To page
9567
Abstract
The addition of TMSCN to a variety of arylaldimines (Strecker reaction) in the presence of LiClO4 or BF3·Et2O in acetonitrile has been studied. The reaction provided the addition products in very high yields. The method has been successfully utilized for the synthesis of (S)-phenylglycine methyl ester.
Keywords
imines , TMSCN addition , ?-Amino acid
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844266
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