Author/Authors :
Bنurle، نويسنده , , Stefan and Blume، نويسنده , , Thorsten and Leroy، نويسنده , , Emmanuel and Mengel، نويسنده , , Anne and Parchmann، نويسنده , , Christian and Schmidt، نويسنده , , Kathrin and Skuballa، نويسنده , , Werner، نويسنده ,
Abstract :
Ring enlargement of ansa-steroids leads to a variety of novel templates which are suitable for the preparation of diverse libraries of natural product derivatives. Key steps for the synthesis of these highly functionalized templates were either an ozonolysis-derivatization-ring closing metathesis-sequence or a macrolactonization.
Keywords :
Ring closing metathesis , Steroids , Macrocycles , macrolactonization , template
