Title of article
Synthesis of 2-oxazolines mediated by N,N′-diisopropylcarbodiimide
Author/Authors
Crosignani، نويسنده , , Stefano and Young، نويسنده , , Abigail C. and Linclau، نويسنده , , Bruno، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
9611
To page
9615
Abstract
N-(β-Hydroxy)amides can be cyclised by reaction with diisopropylcarbodiimide (DIC) to give the corresponding 2-oxazolines in high yields. The reaction requires only very mild Lewis-acid catalysis (5 mol % Cu(OTf)2) and can be accomplished with simple heating, or in very short reaction times under microwave irradiation.
Keywords
Lewis acid , microwave irradiation , 2-Oxazoline , Carbodiimide , Isourea
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844287
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