Title of article :
Bioluminescence activity of Latia luciferin analogues: replacement of the 2,6,6-trimethylcyclohexene ring onto the methyl-substituted phenyl groups
Author/Authors :
Nakamura، نويسنده , , Mitsuhiro and Mamino، نويسنده , , Masashi and Masaki، نويسنده , , Mizuki and Maki، نويسنده , , Shojiro and Matsui، نويسنده , , Ryo and Kojima، نويسنده , , Satoshi and Hirano، نويسنده , , Takashi and Ohmiya، نويسنده , , Yoshihiro and Niwa، نويسنده , , Haruki، نويسنده ,
Abstract :
A series of Latia luciferin analogues having methyl-substituted phenyl groups instead of the natural 2,6,6-trimethylhexene ring was synthesized and their bioluminescence activity were measured. The Latia luciferase was found to be able to moderately recognize the appropriately methyl-substituted phenyl analogues with the same light production kinetics as that of natural luciferin.
Keywords :
Latia neritoides , luciferin , luciferase , Bioluminescence
