Author/Authors :
Flanigan، نويسنده , , David L. and Yoon، نويسنده , , Cheol Hwan and Jung، نويسنده , , Kyung Woon، نويسنده ,
Abstract :
Highly functionalized chiral γ-lactams are efficiently synthesized via Rh(II) catalyzed intramolecular C–H insertion from various α-diazoamides. Independent of α-substituents, regio- and stereoselectivities are enhanced through a conformational effect exerted by a bicyclic transition state.
