Title of article
Photooxygenation of 3-aryl-2-cyclohexenols: synthesis of a new series of antimalarial 1,2,4-trioxanes
Author/Authors
Singh، نويسنده , , Chandan Ashis Gupta، نويسنده , , Nitin and Puri، نويسنده , , Sunil K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
205
To page
207
Abstract
Using easily accessible 3-aryl-2-cyclohexenols, a photooxygenation route for the preparation of bicyclic 1,2,4-trioxanes is reported. Several of these trioxanes have shown significant antimalarial activity against multidrug resistant Plasmodium yoelii in mice by the oral route.
Keywords
Plasmodium yoelii , Photooxygenation , antimalarial , 1 , 2 , 4-trioxane
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844392
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