Title of article
A stannylene strategy for regioselective acylation and phosphorylation of 1,2-cyclohexylidene-myo-inositol. Its convenient resolution and phosphatidylinositol synthesis
Author/Authors
Watanabe، نويسنده , , Yutaka and Kiyosawa، نويسنده , , Yoko and Hyodo، نويسنده , , Sayuri and Hayashi، نويسنده , , Minoru، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
281
To page
284
Abstract
The bis(dibutylstannylene) derivative of 1,2-cyclohexylidene-myo-inositol reacted with (S)-O-acetylmandeloyl chloride and diphosphate tetraesters to give 3,6-dimandelate and 3-phosphate, respectively. Using the stannylene methodology for the optical resolution and regioselective phosphorylation of the ketal, a concise synthesis of phosphatidylinositol with the natural configuration was accomplished.
Keywords
Optical resolution , Phosphatidylinositol , O-Acetylmandelic ester , Selective phosphorylation , Myo-inositol , Cyclohexylidene-myo-inositol , Stannylene derivative
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844424
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