Title of article
The Overman rearrangement in carbohydrate chemistry: stereoselective synthesis of functionalized 3-amino-3,6-dihydro-2H-pyrans and incorporation in peptide derivatives
Author/Authors
Montero، نويسنده , , Ana and Mann، نويسنده , , Enrique and Herradَn، نويسنده , , Bernardo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
401
To page
405
Abstract
A stereocontrolled synthesis of an unsaturated sugar bearing two amino groups (one of them masked as an azide), using an Overman rearrangement as key step, is described. This scaffold is used to prepare two peptides having aromatic fragments, which have shown activity as calpain inhibitors.
Keywords
Amino sugar , Calpain inhibitor , Enkephalin , Overman rearrangement , Peptidomimetic
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844470
Link To Document