Author/Authors :
Moon، نويسنده , , Man Sik and Jun، نويسنده , , Sook Jin and Lee، نويسنده , , So Ha and Cheong، نويسنده , , Chan Seong and Kim، نويسنده , , Kwan Soo and Lee، نويسنده , , Byung Suk، نويسنده ,
Abstract :
Garamine derivative, key intermediate, was obtained from acid cleavage of sisomicin derivative. Its subsequent product was glycosylated with 6-azido-2,3,4-tri-O-benzyl-6-deoxy-α-d-glucopyranosyl chloride using silver triflate as a promoter to give isepamicin.
Keywords :
aminoglycoside , antibiotics , Isepamicin , Garamine
