Title of article
Novel and convenient synthesis of 4(1H)quinolones
Author/Authors
Tois، نويسنده , , Jan and Vahermo، نويسنده , , Mikko and Koskinen، نويسنده , , Ari، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
735
To page
737
Abstract
A rapid two-step synthesis of 4(1H)quinolones is described. The first step involves condensation of o-nitroacetophenone with N,N-dimethylformamide dimethylacetal yielding highly crystalline enamines. In the second step a reductive cyclization is achieved under catalytic transfer hydrogenation (CTH) conditions. In all cases, the total time of this process was less than 3 h.
Keywords
Quinolones , Leimgruber–Batcho , Pd catalysis
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844601
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