Title of article
Synthesis of regiospecifically substituted quinolines from anilines
Author/Authors
Giorgio Chelucci، نويسنده , , Giorgio and Manca، نويسنده , , Ilaria and Pinna، نويسنده , , Gerard A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
767
To page
770
Abstract
A protocol for the synthesis of quinolines substituted on both pyridine and benzo-fused rings is reported. The method is based on the formylation of a substituted N-(tert-butoxycarbonyl)aniline followed by direct cyclisation and aromatisation of the intermediate product obtained by condensation of the formed N-Boc o-aminobenzaldehyde with an enolisable carbonyl compound. Yields up to 88% have been obtained.
Keywords
Nitrogen Heterocycles , Quinolines , Formylation , Azaannulation
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844615
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