Title of article
Domino functionalizations of the amino terminus of 6-aminopenicillanates with Ph3PCCO
Author/Authors
Schobert، نويسنده , , Rainer and Stangl، نويسنده , , Andreas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
1127
To page
1130
Abstract
6-Aminopenicillanates, or the sulfoxides or the sulfones thereof, were N-acylated in a three-component reaction with an aldehyde and Ph3PCCO to give the corresponding 6-(E-2′-alkenoyl)amides. This domino addition–Wittig alkenation sequence was extended by an additional Claisen rearrangement step in the side-chain in the case of 5g.
Keywords
?-Lactams , Phosphorus ylides , Wittig alkenation , Domino reaction
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844759
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