Title of article
Total synthesis of the antitumor active pyrrolo[2,1-a]isoquinoline alkaloid (±)-crispine A
Author/Authors
Gabriele and Knِlker، نويسنده , , Hans-Joachim and Agarwal، نويسنده , , Sameer، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
1173
To page
1175
Abstract
Addition of a propargyl Grignard reagent to 3,4-dihydro-6,7-dimethoxyisoquinoline, silver(I)-promoted oxidative cyclization, and chemoselective hydrogenation of the pyrrole ring provide a simple three-step route to the antitumor active pyrrolo[2,1-a]isoquinoline alkaloid (±)-crispine A.
Keywords
pyrroles , total synthesis , Alkaloids , Hydrogenation
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844782
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