Author/Authors :
Sasaki، نويسنده , , Shigeru and Yamauchi، نويسنده , , Takayasu and Kubo، نويسنده , , Hajime and Kanai، نويسنده , , Masatomi and Ishii، نويسنده , , Akihiro and Higashiyama، نويسنده , , Kimio، نويسنده ,
Abstract :
Treatment of an equimolar mixture of trifluoromethylketones (TFMKs) and methylketones (MKs) with Et2Zn resulted in selective reduction of the TFMKs in good yield. In contrast, treatment of an equimolar mixture of TFMKs and MKs with NaBH4 in the presence of CeCl3 in EtOH/H2O (10:1) at −10 °C reduced only the MKs.
Keywords :
chemoselective reduction , Trifluoromethylketones , Methylketones , Diethylzinc
