1,2,3,4,5,6-Hexahydrophosphinine 1-oxides with an exocyclic P-function at position 3: diastereoselective synthesis, stereostructure and conformation

Catalytic hydrogenation of the corresponding tetrahydrophosphinine oxides afforded the title compounds (4–6) as exclusive or major diastereomers the stereostructure and conformation of which were evaluated by stereospecific 3J couplings, as well as HF/6-31G* ab initio calculations.