Title of article
Enantioselective Morita–Baylis–Hillman (MBH) reaction promoted by a heterobimetallic complex with a Lewis base
Author/Authors
Matsui، نويسنده , , Katsuya and Takizawa، نويسنده , , Shinobu and Sasai، نويسنده , , Hiroaki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
1943
To page
1946
Abstract
A new double-activation catalysis is presented for the Morita–Baylis–Hillman (MBH) reaction of an α,β-unsaturated ketone and an aldehyde by the combined use of a heterobimetallic asymmetric complex and tributylphosphine ((n-Bu)3P) to afford the α-methylene-β-hydroxy ketone with up to 99% ee.
Keywords
Morita–Baylis–Hillman (MBH) reaction , Double-activation
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845109
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