Mucohalic acid in Lewis acid catalyzed Mukaiyama aldol reaction: a concise method for highly functionalized γ-substituted γ-butenolides
Author/Authors :
Angell، نويسنده , , Paul J. Zhang، نويسنده , , Ji and Belmont، نويسنده , , Daniel and Curran، نويسنده , , Timothy N. Davidson، نويسنده , , James G.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Pages :
4
From page :
2029
To page :
2032
Abstract :
The first Mukaiyama aldol reaction on mucohalic acid (1a/b) has been achieved. Reaction of 1 with various ketene silyl acetals or silyl enol ethers in the presence of a Lewis acid provides the γ-substituted γ-butenolides in good to excellent yield.
Keywords :
Mucohalic acid , Mukaiyama aldol , butenolides , Lewis acid
