Title of article
Highly reactive and enantioselective kinetic resolution of terminal epoxides with H2O and HCl catalyzed by new chiral (salen)Co complex linked with Al
Author/Authors
Thakur، نويسنده , , Santosh Singh and Li، نويسنده , , Wenji and Kim، نويسنده , , Seong-Jin and Kim، نويسنده , , Geon-Joong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
2263
To page
2266
Abstract
The asymmetric hydrolytic kinetic resolution (HKR) of racemic terminal epoxides by new easily synthesized dimeric chiral (salen)Co bearing Al, provides a practical and straightforward method for the synthesis of enantiomerically enriched terminal epoxides (>99% ee) and diols. An inorganic acid, HCl is applied first time for the asymmetric ring opening reaction of terminal epoxides. Reactions are conveniently carried out at room temperature under an air atmosphere.
Keywords
Terminal epoxides , Chiral cobalt salen catalyst , kinetic resolution , Asymmetric ring opening reactions
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845224
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