Title of article :
Reaction of a 5α-bromo-6β,19-epoxysteroid with BF3·Et2O/Ac2O: An evidence of a cyclic bromonium cation
Author/Authors :
Iglesias-Arteaga، نويسنده , , Mart??n A. and Ledesma-Rodr??guez، نويسنده , , Fanny L. and Méndez-Stivalet، نويسنده , , José M. and Flores-Alamo، نويسنده , , Marcos، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Treatment of 3β-acetoxy-5-bromo-6β,19-epoxy-5α-androstan-17-one with Ac2O and BF3·OEt2, produced the cleavage of the epoxy moiety and migration of the bromine atom to afford 3β,19-diacetoxy-6α-bromo-5-hydroxy-5β-androst-17-one in high yield.
Keywords :
19-epoxysteroid , 5?-Bromo-6? , Bromine migration , Cyclic bromonium , Diequatorial bromohydrin , 5?-Hydroxy-6?-bromosteroid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
