• Title of article

    Palladium-catalyzed cross-coupling reaction of alkynylzincs with benzylic electrophiles

  • Author/Authors

    Qian، نويسنده , , Mingxing and Negishi، نويسنده , , Ei-ichi، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    2927
  • To page
    2930
  • Abstract
    The reaction of alkynylzinc bromides with benzyl bromides or chlorides in the presence of a catalytic amount of Pd(DPEphos)Cl2 in THF at 23 °C cleanly produces the corresponding benzylated alkynes in 73–97% yields. With 10−3 mol % of Pd(DPEphos)Cl2, the maximum turnover number of 7.1 × 104 has been observed for the formation of PhCCCH2Ph.
  • Keywords
    Palladium-catalyzed cross-coupling , Alkynylzincs , Benzylic electrophiles , Benzylated alkynes , Pd(DPEphos)Cl2
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2005
  • Journal title
    Tetrahedron Letters
  • Record number

    1845458

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1845458